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£71.99

Transmembrane Traffic of Metals in the Epidermis as a Phenomenon of Self-Organisation

By: Valery Ivanovich Petukhov, Egor Vladimirovich Dmitriev

£71.99

This study of trace elements in human hair challenges the widespread belief that metal concentration in hair reflects its content in the whole organism. Such extrapolation is not only unreasonable but potentially dangerous, as it can lead to diagnostic and therapeutic errors.

The monograph presents the results of the study of homeostasis of trace elements in human hair. Statistical analysis of extensive data sets containing concentrations of…
£71.99
£71.99
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The monograph presents the results of the study of homeostasis of trace elements in human hair. Statistical analysis of extensive data sets containing concentrations of metals in this biosubstrate in different groups of healthy people has been carried out. The authors failed to confirm the correctness of the stable and widespread in modern elementology opinion that by the level of concentration of this or that metal in hair it is possible to make judgements about its content in the whole organism. Such extrapolation is not only unreasonable, but also potentially dangerous, as it can lead to diagnostic and therapeutic-corrective errors. Furthermore, evidence has been obtained that metal-ligand homeostasis in an epidermal derivative (hair) is associated with self-organised criticality (SC) phenomena. Thus, shifts in metal homeostasis in hair spectrometry (to avoid unwarranted generalisations) should be attributed only to this substrate (hair).

Valery Ivanovich Petukhov is a Medicine Sciences Doctor and Emeritus Professor of the Baltic International Academy, Riga, Latvia.
He has more than 50 years of experience in clinical work as a therapeutist – hematologist, and has spent more than 35 years as a teaching staff of clinical hematology and therapy in medical higher educational institutions. He has published more than 180 scientific works, including 4 monographs: “Kinetic basis in prognosis of survival in chronic myeloid leukemia”, 1995; “Alfa-interferon in the oncohematology”, 2000; “Geriatric hematology”, 2012 (as coauthor); “Metal-ligand homeostasis in epidermic cells”, 2015. His spheres of scientific research work include: clinical haematology, clinical biochemistry, and bioelementology.

Egor Vladimirovich Dmitriev, PhD, is a senior scientist at the Marchuk Institute of Numerical Mathematics of the Russian Academy of Sciences, Moscow, Russia. He specialises in Statistical modelling and data processing. His current research interests are: Remote sensing, pattern recognition, thematic processing of remote sensing imagery and LiDAR data. Egor V. Dmitriev is the author and co-author of over 100 publications in peer-reviewed scientific journals.

Hardback

  • ISBN: 1-0364-4305-1
  • ISBN13: 978-1-0364-4305-4
  • Date of Publication: 2025-06-24

Ebook

  • ISBN: 1-0364-4306-X
  • ISBN13: 978-1-0364-4306-1
  • Date of Publication: 2025-06-24

Subject Codes:

  • BIC: MBGR, MJ, MJD
  • THEMA: MBGR, MJ, MJD
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