Calcium Study to Alzheimer’s Therapeutics

Seung Hyun Yoo, PhD was born in the Republic of Korea and graduated from Seoul National University, Seoul, Republic of Korea as a zoology major. He has a PhD in Chemistry from the University of Texas, Austin, USA. He has worked on chromogranin A and the IP3-sensitive Ca2+ store role of secretory granules at the University of Texas Southwestern Medical Center, Dallas, USA, as well as the National Institutes of Health, Maryland, USA, where he continued to work on chromogranins A and B as a principal investigator. Seung Hyun Yoo later returned to Republic of Korea to work at the Korea Advanced Institute of Science and Technology and thereafter at Inha University Medical School in Incheon, as biochemistry professor. Here he discovered the IP3-sensitive nucleoplasmic Ca2+ storage and control organelle. After retiring from Inha and starting a biotech startup, he identified granin proteins as the pathogenic target of Alzheimer’s disease and developed Alzheimer’s therapeutics.