New-Delhi metallo-β-lactamase (NDM) is a chimeric enzyme containing among the most worrying bacterial resistance markers. This book reviews knowledge from all concerned areas, and links the knowledge to display a full picture of NDM.
Chemists, physicians, why biologists, will discover why particular genetic features caused the anchoring of NDM to the outer membrane, and endow it with the capacities to overcome scarce zinc conditions, more stability, and fast transfer. Starting from its discovery in India, tracking it throughout the world, this book will describe its mechanism, and highlight the assets brought by each mutation.
This review aims to gather all information about NDM from any research field, and to explain causes and consequences in a language understandable for all scientists.
The use of glycated haemoglobin was a major step in antidiabetic treatment and led to the identification of cell receptors. The aim of this study is to explore how one such cell receptor, RAGE, offers new therapeutic possibilities for diabetes, ageing, and Alzheimer’s disease.
